Structural Biology Platform Laboratory

Introduction

The structural biology platform has built a complete technical chain of efficient protein expression, purification, preparation, protein property identification and structural biology research, realizing low-cost, high-throughput and accurate protein structural and functional research and service capabilities, and giving full supporting in protein structural and functional research. The platform includes protein expression preparation, property identification and structural biology research modules, and has a technical supporting team with rich experiences. Equipped with complete structural...

Group Leader/Executive Director

LIU Weidong, Ph.D., Professor and Doctoral Supervisor. He is currently the director of Structural Biology Platform Laboratory of Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, and was selected as a member of Youth Innovation Promotion Association of Chinese Academy of Sciences. He has published more than 60 research papers in SCI journals such as Nature Communications, Angew Chem and ACS Catalysis. He presided over many key research and development projects, National Natural Science Foundation and other projects, and won the second prize of Natural Science in Ti...

team leader:LIU Weidong

Research Direction and Content more+

Structural Biology Platform Laboratory is mainly divided into the following modules, each module has completely large-scale equipment and mature advanced technology, and each module complements each other to form a complete technical chain of protein structural research. The platform provides the following parts of instrument and equipment support services and technological research and development services:

Representative Achievements more+

(1) Developing protein expression and purification technology system: Aiming at the problems of protein expression and purification, the platform has developed a variety of expression vectors and host libraries, and built efficient milligram to gram protein expression and purification technology, which have improved the efficiency of protein expression and purification.

Research Progress more+

Research Projects more+

The team has undertaken various scientific research tasks, including Synthetic Biology Project of the National Key R&D Plan, the General Projects of National Natural Science Foundation of China, the Strategic Pilot Science and Technology Project of Chinese Academy of Sciences, and the Tianjin Synthetic Biotechnology Innovation Ability Improvement Action.