President's mail  |   Contact  |   CAS  |   中文  |   Sitemap     
  Location: Home >> Int’l Cooperation >> Int'l Cooperation News
Professor Irene Wagner-D?bler from the German Helmholtz Centre for Infection Research (HZI) gives lecture at TIB
  Time:2013-11-22

Professor Irene Wagner-Döbler from German Helmholtz Centre for Infection Research (HZI) visited TIB at the invitation of Professor Jibin Sun on July 30th and she gave a presentation titled "Systems biology of Streptococcus mutans for drug development".

In the presentation, Professor Irene Wagner-Döbler introduced streptococcus mutans which is a major  pathogen group of human dental plaque and she elaborated the mechanism that biofilm inhibitors Carolacton inhibiting and killing Streptococcus mutans .Subsequently, she also described the current research results : Through transcriptome sequencing and background literature research, further identified serine - threonine protein kinase (PknB) is the key gene in the cracking process of Streptococcus mutans. Detected PknB and its downstream gene expression and regulation by using a fluorescent reporter gene, and found expression of PknB itself remained constant, a large number of key genes downstream regulated by pknB.

After the lecture, Professor Irene Wagner-Döbler and the researchers in the Institute made communication and discussion on the latest research results, which broadened the research ideas between the two sides on systems biology.

32 West 7th Avenue, Tianjin Airport Economic Area, Tianjin 300308, China
Tel: 022-84861997/84861977 Fax: 022-84861926 E-mail: tib_zh(AT)tib.cas.cn
Copyright @2013, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences