Education

1997-2001    Agricultural University of Hebei, Baoding, China, B. Sc

2001-2004    Agricultural University of Hebei, Baoding, China, M. Sc

2004-2007    Institute of Microbiology, Chinese Academy of Sciences, Beijing, China, DPhil

Professional Experience

2008-2011      Career development Fellow, National Institute for Medical Research, MRC, London, UK

2011-present  Associate Investigator, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China

Research Interest

Haixia Xiao is interested in the study of molecular virology, and developing vaccines against different pathogens, especially for influenza viruses. She also focuses on the screening of human monoclonal antibodies which can function as therapeutic vaccines to cure patients by neutralizing pathogens.

Selected Publications

1.       Xiong†, X., Coombs†, PJ., Martin†, RS., Liu, J., Xiao, H., McCauley, JW., Locher, K., Walker, PA., Collins, P., Kawaoka, Y., Skehel, JJ., Gamblin*, JS. (2013) Receptor binding by a ferret-transmissible H5 avian influenza. Nature, 497 (7449): 392-396.

2.        Liu, D†., Shi, W†., Shi, Y., Wang, D., Xiao, H., Li, W., Bi, Y., Wu, Y., Li, X., Yan, J., Liu, W., Zhao, G., Yang, W., Wang, Y., Ma, J., Shu, Y*., Lei, F*., Gao, GF*. (2013) Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet, 381(9881):1926-1932.

3.        Li, J†., Yu, X†., Pu, X†., Xie, L†., Sun, Y†., Xiao, H., Wang, F., Din, H., Wu, Y., Liu, D., Zhao, G., Liu, J*., Pan, J*. (2013) Environmental connections of novel avian-origin H7N9 influenza virus infection and virus adaptation to the human. Science China: Life Sciences, 56(6):485-492

4.         Lu, X., Shi, Y., Gao, F., Xiao, H., Wang, M., Qi, J., Gao*, G. F. Insights into avian influenza virus pathogenicity: the hemagglutinin precursor HA0 of H16 subtype has an a-helix structure in its cleavage site with an inefficient HA1/HA2 cleavage. Journal of Virology, 86 (23): 12861-128.

5.        Iqbal*, M., Essen, SC., Xiao, H., Brookes, SM., Brown, IH., McCauley*, JW. (2012) Selection of variant viruses during replication and transmission of H7N1 viruses in chickens and turkeys. Virology, 433 (2): 282-295.

6.      Xuan, C., Shi, Y., Qi, J., Zhang, W., Xiao, H., Gao*, G. F. (2011) Structural vaccinology: Structure-based design of influenza A virus Hemagglutinin (HA) subtype-specific subunit vaccines. Protein & cell, 2(12):997-1005.

7.      Song†, XH., Xiao†, H., Huang, Y†., Fu, G., Jiang, B., Kitamura, Y., Liu, W., Liu, D., Gao*, G. F. (2010) Serological surveillance of influenza A virus infection in swine populations in Fujian province, China: no evidence of naturally occurring H5N1 infection in pigs. Zoonoses Public Health, 57(4):291-298.

8.       Iqbal, M., Xiao, H., Baillie. G., Warry, A., Essen, SC., Londt, B., Brookes, SM., Brown, IH., McCauley*, JW. (2009) Within-host variation of avian influenza viruses. Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1530):2739-2747.

9.       Guo†, Y., Rumschlag-Booms†, E., Wang†, J., Xiao, H., Yu, J., Wang, J., Guo, L., Gao, G. F., Cao, Y., Caffrey, M., Rong*, L. (2009) Analysis of hemagglutinin-mediated entry tropism of H5N1 avian influenza. Virology Journal, 6:39.

10.     Liu*†, J., Xiao†, H., Lei†, F., Zhu, Q., Qin, K., Zhang, X. W., Zhang, X. L., Zhao, D., Wang, G., Feng, Y., Ma, J., Liu, W., Wang, J., Gao*, G. F. (2005) Highly pathogenic H5N1 influenza virus infection in migratory birds. Science, 309 (5738): 1206