2008-Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Professor;
Our group focuses on effective utilization of bioresources and production of bioactive substances, such as rare sugar, polyol,polysaccharide, bioactive peptide, and sugar-protein complex. We are using enzyme and biocatalysis engineering technology to develop these functional sugars and bioactive peptides as food additives. We have also contributed structural and functional support to a project of glycated proteins aimed at characterizing important sugar-protein complexes. We are aiming to increase our screening capacity to rare sugar transforming enzyme by traditional method combined with genetic mining. The mission of the lab is to establish an biocatalysis technical platform for transforming the bioresources into the novel active substance. The research interests includes 1) the development and utilization of functional rare sugar;2)the study of the sugar-protein complex and protein modification; 3)the application of natural bioactive component in functional food.
1.Sun Y., Hayakawa S., Guan Y. (2011) Evaluation of angiotensin ACE inhibitory activities of hydrolysaates generated from byproducts of freshater clam. Food Sci. Biotechnol. 20, 303-310.
2.Li Y., Zhu Y., Liu A., Sun Y. (2011) Identification and characterization of a novel L-arabinose isomerase from Anoxybacillus flavithermus useful in D-tagatose production. Extremophiles, 15, 441-450.
3.Zeng, Y., Zhang X., Guang Y., Sun Y. (2011) Characteristics and antioxidant activity of Maillard reaction products from psicose-lysine and fructose-lysine model systems. J. Food Sci., 76, 398-403.
4.Zeng Y., Zhang X., Guan Y., Sun Y. (2012) Enzymatic hydrolysates from tuna backbone and the subsequent Maillard reaction with different ketohexoses. International. J. Food Sci. Technol. 47(6), 1293-1301.
5.Chan H., Zhu Y., Hu Y., Ko T., Huang C., Ren F., Chen C., Ma Y., Guo R., Sun Y. (2012) Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. Protein &Cell 3, 123-131.
6.Zhu Y., Men Y., Bai W., Li X., Sun Y., Ma Y. (2012) Overexpression of D-psicose 3-epimerase from Ruminococcus sp. In Escherichia coli and its prospect for D-psicose production. Biotechnology Letters, 34(10), 1901-1906.
7.Zeng Y., Zhang H., Guan. Y, Zhang L., Sun Y. (2013) Comparative study on the effects of D-psicose and D-fructose in the Maillard reaction with β-lactoglobulin. Food Sci. Biotech. 22, 341-346.
8.Li X., Zhu Y., Zeng Y., Zhang T., Sun Y. (2013) Overexpression D-psicose 3-epimerase from Clostridium cellulolyticum H10 in Bacillus subtilis and its prospect for d-psicose production.Adv. J. Food Sci. Tech. 5, 264-269.
9.Men Y., Zhu Y., Zhang L., Kang Z., Izumori K. Sun Y., Ma Y. (2012), Enzymatic conversion of D-galactose to D-tagatose: Cloning, overexpression and characterization of L-arabinose isomerase from food-grade microorganism Pediococcus pentosaceus. Microbiol Res.
10. Hishiike1 T., Ogawa1 M., Hayakawa1 S., Nakajima D., Ooshima H., Sun Y. (2013) Transepithelial transports of rare sugar D-Psicose in human intestine. J. Agric. Food Chem.61, 7381-7386.
11. Han W., Zhu Y., Men Y., Yang J., Liu C., Sun Y. (2013) Production of Allitol from D-Psicose by a novel isolated strain of Klebsiella oxytoca G4A4. J. Basic Microbiol. In press.
12. Sun Y., Li Y., Song H., Zhu Y.《Natural Antimicrobials in Food Safety and Quality》, Ed. Dr.Mahendra Rai, Published by CAB International；Chapter No.6, “Microbial Fermentation for Food Preservation”, 2011, 9. 77-94.
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