Her research pprimarily focuses on the microbial synthesis of natural products guided by synthetic biology. Concentrate on yeast chassis, employing the mining and engineering of key enzymes, along with the design and optimization of metabolic pathways, to construct efficient cell factories for the biomanufacturing of functional microbial metabolites.

Education

2012.09 to 2018.06, PhD, College of Biotechnology, Tianjin University of Science & Technology

2008.09 to 2012.06, Bachelor, College of Life Sciences, Liaocheng University

Professional Experience

2025.10 to present, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Associate Professor

2024.12 to 2025.09, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Research Associate

2020.01 to 2024.11, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Postdoc

2018.07 to 2019.12, Disha Pharmaceutical Group Co., Ltd., R&D Project Team Leader

1. Liqiu Su^#, Pi Liu^#, Weidong Liu, Qi Liu, Jian Gao, Quanlu Zhao, Kaizhi Jia, Xiang Sheng, Hongwu Ma, Qinhong Wang,* and Zongjie Dai*. Computational design-enabled divergent modification of monoterpene synthases for terpenoid hyperproduction. ACS Catalysis, 2024, 14, 17699−17715.

2. Ying Chen^#, Liqiu Su^#, Qi Liu, Ge Zhang, Hongyang Chen, Qinhong Wang, Kaizhi Jia*, Zongjie Dai*. Triune engineering approach for (+)-valencene overproduction in Yarrowia lipolytica. Biotechnology Journal. 2025 Jan;20(1):e202400669.

3. Amna Bibi，苏立秋*，戴宗杰*，王钦宏。萜类化合物微生物合成中酶工程的研究进展与展望。生物工程学报. 2024, 40(8): 2473-2488.

4. Liqiu Su, Yanbing Shen*, Zhiyan Liu, Xuening Sheng, Yanan Zhu, Jianxin Wang, Jingjing Liu, Min Wang*. Effects of palygorskite on steroid-transformation in Mycobacterium neoaurum. Applied Clay Science, 2023, 233, 106839.

5. Qi Liu, Ge Zhang, Liqiu Su, Pi Liu, Shiru Jia, Qinhong Wang and Zongjie Dai*, Reprogramming the metabolism of oleaginous yeast for sustainably biosynthesizing the anticarcinogen precursor germacrene A. Green Chemistry, 2023, 25, 7988-7997.

6. Yufeng Guo, Liqiu Su, Qi Liu, Yan Zhu*, Zongjie Dai*, Qinhong Wang. Dissecting carbon metabolism of Yarrowia lipolytica type strain W29 using genome-scale metabolic modelling. Computational and Structural Biotechnology Journal, 2022, 20, 2503-2511.

7. 苏立秋，张歌，姚震，梁配新，戴宗杰*，王钦宏. 非传统酵母代谢工程研究进展。生物工程学报. 25, 2021, 37(5): 1659-1676.

8. Liqiu Su, Shuangping Xu, Yanbing Shen*, Menglei Xia, Xiaoxian Ren, Lifang Wang, Zhihua Shang, Min Wang*. The sterol carrier hydroxypropyl-β-cyclodextrin enhances the metabolism of phytosterols by Mycobacterium neoaurum. Applied and Environmental Microbiology, 2020, 86(15), e00441-20.

9. Liqiu Su, Yanbing Shen*, Menglei Xia, Zhihua Shang, Shuangping Xu, Xingjuan An, Min Wang*. Overexpression of cytochrome p450 125 in Mycobacterium: a rational strategy in the promotion of phytosterol biotransformation. Journal of Industrial Microbiology and Biotechnology, 2018, 45(10), 857-867.

10. Liqiu Su, Yanbing Shen*, Wenkai Zhang, Tian Gao, Zhihua Shang, Min Wang*. Cofactor engineering to regulate NAD⁺/NADH ratio with its application to phytosterols biotransformation. Microbial Cell Factories, 2017, 16.

11. Liqiu Su, Yanbing Shen*, Tian Gao, Jianmei Luo, Min Wang*. Improvement of AD biosynthesis and cofactors analysis response to enhanced oxygen transfer by oxygen vectors in Mycobacterium neoaurum TCCC11979. Applied Biochemistry and Biotechnology, 2017, 182(4), 1564-1574.