My interest is in metabolic control fermentation of amino acids. The primary aim of my work is to develop high-throughput automatic fermentation technologies to appropriately assess the fermentation performance of genetically engineered microorganisms, and to further modify the automatic processes adaptive to the various phenotypic characteristics of the novel mutants with unknown genetic characteristics or directed genome modifications. I also focus on the development of product extraction process and industrial scale-up fermentation. To date, I have published more than ten research papers in international journals, and applied for over twenty Chinese invention patents and 4 PCT patents, in which more than half are granted.

2010 to 2013, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China, M.S. in Fermentation Engineering

2013 to 2021, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Engineer

2021 to present, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Senior Engineer

1. Zhao J#, Liu C#, Guo X#, Wang J, Liu H, Zheng P, Sun J, Ma YH. Efficient production of trans-3-hydroxyproline by a bacterial trans-3-proline hydroxylase and characterization of enzymatic properties. Biochem Eng J, 2019, 147: 57-61.

2. Chen JZ, Wang Y, Guo X, Rao DM, Zhou WJ, Zheng P, Sun JB, Ma YH. Efficient bioproduction of 5-aminolevulinic acid, a promising biostimulant and nutrient, from renewable bioresources by engineered Corynebacterium glutamicum. Biotechnol Biofuels, 2020,13: 41.

3. Jiao Liu, Moshi Liu, Tuo Shi, Guannan Sun, Ning Gao, Xiaojia Zhao, Xuan Guo, Xiaomeng Ni, Qianqian Yuan, Jinhui Feng, Zhemin Liu, Yanmei Guo, Jiuzhou Chen, Yu Wang, Ping Zheng & Jibin Sun. CRISPR-assisted rational flux-tuning and arrayed CRISPRi screening of an L-proline exporter for L-proline hyperproduction. NATURE COMMUNICATIONS, 2022,13:891.

Over ten projects I have undertaken are as follows. Sub-project of National Key R&D Program of China, Synthetic Biotechnology Innovation Ability Enhancement Initiative Innovative Talent/Team Development Program of Tianjin, National Natural Science Foundation of China (General Program), Key R&D Project of Shandong Province, and several projects funded by enterprises.