Professor
Huang Zhiyong

Title:Huang Zhiyong

Tel:0086-22-84861931

E-mail:huang_zy@tib.cas.cn

Research Interest

Mainly studying the theories and application technologies of environmental microbiology and microbial ecology. Based on a full understanding of the principles of microbial species interaction, by studying microbial metabolic networks, developing microbial combinatorial techniques and application processes, and applying them to fields such as environmental governance, ecological agriculture, and human health.

Including:

1. Environmental microorganisms and environmental governance technology

2. Agricultural Microbial Technology

3. Intestinal microbiota and heart failure 

Education & Professional Experience

2014-2019 University of Lanzhou,Geological microorganisms, Ph. D.  

1999-2000 The University of Tokyo, bioengineering,Mater degree

1991-1995 Xiamen University, marine biology, Bachelor's degree

Selected Publications

Articles(In the past 5 years)

1. Peng Wu, Qianqian Yuan, Tingting Cheng , Yifan Han, Wei Zhao, Xiaoping Liao, Lu Wang , Jingyi Cai , Qianqian He, Ying Guo, Xiaoxia Zhang, Fuping Lu, Jingjing Wang, Hongwu Ma and Zhiyong Huang. Genome sequencing and metabolic network reconstruction of a novel sulfur-oxidizing bacterium Acidithiobacillus Ameehan. Frontiers in Microbiology. 2023, IF: 5.2

2. Meruyert O. Bauenova, Assemgul K. Sadvakasova, Bekzhan D. Kossalbayev, Yilmaz, Zhiyong Huang, Jingjing Wang, Huma Balouch, Dilnaz E. Zaletova, Mariya A. Lyaguta, Hesham F. Alharby, Suleyman I. Allakhverdiev*, Optimising microalgae-derived butanol yield, International Journal of Hydrogen Energy. 2023, IF: 7.139

3. Jingjing Wang, Siqi Zhao, Song Xu, Wei Zhao, Xiaoxia Zhang, Yu Lei, Huanhuan Zhai and Zhiyong Huang*. Co-inoculation of antagonistic Bacillus velezensis FH-1 and Brevundimonas diminuta NYM3 promotes rice growth by regulating the structure and nitrification function of rhizosphere microbiome. Frontiers in Microbiology. 2023, IF: 5.2

4. Zhou Tong, Luqi Kong, Yuexing Zhang, Tianhui Hu, Rongrong Dai, Yilan Wang, Juan Ji, Zhiyong Huang*, Linzhen Hu*. Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway. Bioorganic Chemistry. 2023, IF: 5.3

5. Jia-Yi Li, Jun-Yu Liang, Zhao-Yuan Liu, Yue-Zhao Yi, Jing Zhao, Zhi-Yong Huang* and Jun Chen. Multicopy Chromosome Integration and Deletion of Negative Global Regulators Significantly Increased the Heterologous Production of Aborycin in Streptomyces coelicolor. Marine Drugs, 2023, IF: 5.1

6. Anqi Xiong, Linsen Ruan, Kaiyu Ye, Zhiyong Huang* and Chan Yu*. Extraction of Chitin from Black Soldier Fly (Hermetia illucens)and Its Puparium by Using Biological Treatment. Life, 2023, IF: 3.2

7. Song Xu, Lidan Tao, Jingjing Wang, Xiaoxia Zhang, Zhiyong Huang*. Rapid in-situ aerobic biodegradation of high salt and oily food waste employing constructed synthetic microbiome. Engineering in Life Sciences, 2022, Accepted, IF: 3.405

8. Md. Abuhena, Jubair Al-Rashid, Md. Faisal Azim,Nirmal Chandra Barman, Md. Niuz Morshed Khan, Md. Golam Kabir, NoorainMunimRasul, Zhiyong Huang, Shahina Akter, Md.Amdadul Huq. Optimization of Bacillus subtilis-based fermentation of anaerobic digestate and biohazard-free application in endophyte-assisted hardening of micropropagated plantlets for increasing survivability. Biocatalysis and Agricultural Biotechnology. 2022, 45, IF: 1.086

9. Rong Yang, Zefeng Qin, Jingjing Wang, Xiaoxia Zhang, Song Xu, Wei Zhao and Zhiyong Huang*. The Interactions between Arbuscular Mycorrhizal Fungi and Trichoderma longibrachiatum Enhance Maize Growth and Modulate Root Metabolome under Increasing Soil Salinity. Microorganisms. 2022, 10(5):1042, IF: 4.149

10. Linzhen Hu, Zhenzhen Wang, Zhou Tong, Ping Hu, Luqi Kong, Mengying Luo, Xiao-Nian Li, Yuexing Zhang*, Zhiyong Huang*, and Yonghui Zhang*. Undescribed Meroterpenoids from Hypericum japonicum with Neuroprotective Effects on H2O2 Insult SH-SY5Y Cells Targeting Keap1-Nrf2. Chinese Journal of Chemistry. 2022, 40, IF: 4.067

11. Xueyang Xiao, Zhou Tong, Yuexing Zhang, Hui Zhou, Mengying Luo, Tianhui Hu, Ping Hu, Luqi Kong, Zeqin Liu, Chan Yu, Zhiyong Huang*, and Linzhen Hu. Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1–Nrf2. Marine Drugs. 2022, 20(3), IF: 4.321

12. Nan Xiao, Bing Wang, Jeanne Jinhui Huang, Zhiyong Huang, Liuyang Shi. Aeration strategy based on numerical modelling and the response mechanism of microbial communities under various operating conditions. Journal of Environmental Management, 2022, 310, IF: 5.767

13. Song Xu, Jingjing Wang, Xiaoxia Zhang, Rong Yang, Wei Zhao, Zhiyong Huang*, Yongli Wang. Lacustrine Sediments Bacterial Community Structure Vertical Succession of the Linxia Basin, NE Tibetan Plateau: Significance for Paleoenvironment Reconstruction. Frontiers in Earth Science. 2022, 9, IF: 3.026

14. Zhou Tong, Xueyang Xiao, Yuanayuan Lu, Yuexing Zhang, Ping Hu, Wen Jiang, Hui Zhou, Shixiang Pan, Zhiyong Huang*, and Linzhen Hu. New Metabolites from Aspergillus ochraceus with Antioxidative Activity and Neuroprotective Potential on H2O2 Insult SH-SY5Y Cells. Molecules. 2022, 27(1), 52, IF: 4.927

15. Jingjing Wang, Song Xu, Rong Yang, Wei Zhao, Dan Zhu, Xiaoxia Zhang, Zhiyong Huang*, Bacillus amyloliquefaciens FH‑1 significantly affects cucumber seedlings and the rhizosphere bacterial community but not soil. Scientific Reports, 2021, 11(1), IF:4.130

16. Linzhen Hu, Shuying Tian, Rongrong Wu, Zhou Tong, Wen Jiang, Ping Hu, Xueyang Xiao, Xueke Zhang, Hui Zhou, Qingyi Tong, Yuanyuan Lu, Zhiyong Huang,* Yong Chen, and Yonghui Zhang*. Identification of anti-Parkinson’s Disease Lead Compounds from Aspergillus ochraceus Targeting Adenosin Receptors A2A. ChemistryOpen. 2021, 10: 630-638, IF:2.991

17. Tan Liu, Zhiyong Huang, Xi Gui, Wei Xiang, Yubo Jin, Jun Chen and Jing Zhao*. Multi-omics Comparative Analysis of Streptomyces Mutants Obtained by Iterative Atmosphere and Room-Temperature Plasma Mutagenesis. Frontiers in Microbiology. 2021, 11, IF:5.640

18. Jingjing Wang, Dan Zhu, Siqi Zhao, Song Xu, Rong Yang, Wei Zhao, Xiaoxia Zhang, Zhiyong Huang*. Effect of Liquid Volume and Microflora Source On Degradation Rate And Microbial Community In Corn Stover Degradation. Amb Express, 2021, 11(1), IF:2.674

19. Haiyan Liu, Jingjing Wang, Wei Zhao, Yun Chen, Ning Lv, Zhengbing Yi, Zhiyong Huang*, Rong Yang, Xin Lv. Soil chemical properties drive the structure of bacterial communities in the cotton soil of arid Northwest China. Ecological research. 2021, 36(2), IF:1.681

20. Jingjing Wang, Song Xu, Rong Yang, Wei Zhao, Dan Zhu, Xiaoxia Zhang, Zhiyong Huang*. Bacillus amyloliquefaciens FH‑1 significantly affects cucumber seedlings and the rhizosphere bacterial community but not soil. Scientific Reports. 2021, 11, IF:4.379

21. Wei He, Gen Wang, Yongli Wang⁎, Zhifu Wei⁎, Zhiyong Huang, Ting Zhang, Xueyun Ma,HeMa, Xiaoli Yu. Microbial communities and lipid records of the Linxia Basin, NE Tibetan, Journal of Asian Earth Sciences, 2020, 193, IF:3.449

22. Yifan Han, Bintao Xie, Guangxun Wu, Yaqiong Guo, DeMao Li, Zhiyong Huang*. Combination of Trace Metal to Improve Solventogenesis ofClostridium carboxidivoransP7 in Syngas Fermentation. 2020, Frontiers in Micobiology, 11, IF:5.640

23. Rong Yang, Zefeng Qin, Jingjing Wang, Song Xu, Wei Zhao, Xiaoxia Zhang, Zhiyong Huang*. Salinity changes root occupancy by arbuscular mycorrhizal fungal species. 2020, Pedobiologia, 81-82, IF:1.882

24. Wei Zhao, Jingjing Wang, Song Xu, Yu Lei, Rong Yang R, Liuyang Shi, Xingbiao Wang, Zhiyong Huang*. Bacterioplankton community variation in Bohai Bay (China) is explained by joint effects of environmental and spatial factors. MicrobiologyOpen. 2020. 9(4): e997, IF:3.006

25. Xingbiao Wang, Guilong Wan, Liuyang Shi, Xiaolong Gao1, Xiaoxia Zhang, Xiaoguang Li, Jianfang Zhao, Beibei Sha, Zhiyong Huang*, Direct micro-electric stimulation alters phenanthrene degrading metabolic activities of Pseudomonas sp. strainDGYH-12 in modified bioelectrochemical system, Environmental Science and Pollution Research, 2019, DOI: 10.1007/s11356-019-05670-5), IF:2.767

26. Mingxue Li, Yantao Shi, Yixuan Li, Yizhe Sun, Chunhui Song, Zhiyong Huang, Zongzheng Yang* & Yifan Han*, Shift of microbial diversity and function in high efficiency performance biotrickling filter on gaseous xylene treatment, Journal of the Air & Waste Management Association, 2019, 69(9), IF:1.70

 

Patent(In the past 5 years):

1. A bacterial community gene chip for detecting marine oil spill environments, 2020109451473, invention patent, acceptance date: September 10, 2022

2. A salt-tolerant thermophilic strain and its application in the degradation of kitchen waste oil, 2021108296583, invention patent, acceptance date: July 22, 2021

3. A thermophilic cellulose degrading strain and its application, 2021108296390, invention patent, acceptance date: July 22, 2021

4. A bacterial agent and its application in the in-situ degradation of high salt and oil kitchen waste, 2021108352475, invention patent, acceptance date: July 27, 2021

5. A strain of Enterobacter cloacae with the function of degrading benzopyrene and its application, 2022105571761, invention patent, acceptance date: May 19, 2022

6. A salt-tolerant epichlorohydrin degrading bacterium and its application in treating high salt water bodies, 202210881848.4, invention patent, acceptance date: July 26, 2022

7. An intestinal probiotic and its application in the prevention and treatment of atrial fibrillation, 202211273342.1, invention patent, acceptance date: October 18, 2022

8. A mutated paracoccus with the function of degrading benzopyrene and its application, 202211277301X, invention patent, acceptance date: October 18, 2022

9. A salt tolerant bacterium for synthesizing polyhydroxyfatty acid esters from kitchen waste oil and its application, 2023108326130, invention patent, acceptance date: July 8, 2023

10. A Bacillus strain and its application, 2023110700216, invention patent, acceptance date: August 24, 2023

eleven

12. A thermophilic bacterium producing biological emulsifiers and its application, 2020109103795, invention patent, authorization date: February 18, 2022;

13. A strain of Bacillus amyloliquefaciens and its use, 201910379871.1, invention patent, authorized on October 22, 2021;

14. A method for producing hexanol using low-temperature fermentation of synthetic gas, 201610726716.9, invention patent, authorization date: October 12, 2021;

15. A culture system and method for producing alcohol by anaerobic bacteria using synthetic gas fermentation, 201610726518.2, invention patent, authorization date: October 12, 2021;

16. A culture system and method for producing alcohol by anaerobic bacteria using synthetic gas fermentation, 201610726560.4, invention patent, authorization date: August 24, 2022;

17. A Trichoderma longibrachiatum with broad-spectrum antibacterial properties and its application, 201810439573.2, invention patent, authorization date: August 28, 2022;

18. A biological emulsifier and its application, 201710008577.0, invention patent, authorization date: October 9, 2020;

19. A protein with emulsifying activity and its application, 201710008350.6, invention patent, authorization date: September 18, 2022;

20. A method for regulating the proportion of acid and alcohol in the fermentation products of anaerobic aerobic microorganisms, 201510540079.1, invention patent, authorization date: March 17, 2022;

21. An emulsified protein and its application, 201710008406.8, invention patent, authorized on December 10th, 2019;

22. A method for improving the efficiency of anaerobic aerobic microbial fermentation, 201510534441.4, invention patent, authorization date: December 20, 2019;

23. A culture system and method for producing alcohol through fermentation of anaerobic bacteria containing molybdenum, zinc, and nickel, 201610831710.8, invention patent, authorized on September 6, 2019;

Project

1)  The strategic leading science and technology project of the Chinese Academy of Sciences (Black Land Protection and Utilization Science and Technology Innovation Project Project), XDA28030203, root micro ecological control technology to promote black land protection, 2021/9-2026/83287500 yuan, under research, presided over;

2)  National Key R&D Plan, 2021YFC2102202, Collaborative Metabolism Mechanism of Multiple Pollutants and Construction of Salt tolerant New Ecological Microbial Community under High Salt Stress, 2021/3-2025/23.9 million yuan, under research. Hosting;

3)  Tianjin Synthetic Biotechnology Innovation Capacity Enhancement Action, TSBICIP-PTJS-001, Microbial Metabolic Network Analysis, 2019/11-2022/10, 1 million yuan, under research, hosted;

4)  Key R&D Plan for Synthetic Biology of the Ministry of Science and Technology, 2018YFA0902200, Construction of an Artificial Multicell System for the Transformation and Utilization of Inferior Biomass, 2019/7-2024/61 million yuan, under research, participating;

5)  Key Special Project of the National Key R&D Plan, Evaluation and Application of Intelligent Artificial Degradation System for Soil Pollution Treatment, with a total investment of RMB 61.18 million from July 2019 to July 2024, under research and participation;

6)  Outstanding scientific and technological talent in Binhai New Area, Tianjin, from October 2018 to October 2020, with a total of 472000 yuan, completed and presided over;

7)  Key Project of the National Natural Science Foundation of China, 41831176, Research on Drought of Bioorganic Geochemical Records in the Linxia Basin, Northeast Margin of the Qinghai Tibet Plateau, 2019/1-2023/12, 600000 yuan, under research, participated;

8)  Tianjin Science and Technology Plan Project, 18ZXSZF00100, Biotechnology Research and Development and Post-repair Environmental Assessment for Marine Oil Spill Emergency Response, 2018/10-2021/09, 500000 yuan, completed, participated;

9)  Strategic Biological Resources Plan of the Chinese Academy of Sciences, KFJ-BRP-009, Construction of Microbial Community Bank for Petrochemical Pollution Treatment and Remediation, 2018/7-2019/1, 300000 yuan, concluded, presided over;

10)  Key deployment project of the Chinese Academy of Sciences, KFZD-SW-219, activated sludge function group identification, 2017/10-2019/09, 200000 yuan, concluded, participated;