Title:Wu Xin
Tel:022-24828794
E-mail:wuxin@tib.cas.cn
1. Utilizing the concepts and technologies of synthetic biology to conduct foundational innovation design of animal feed and human food, developing microbial protein sources and functional nutritional resource technologies for applications like single carbon feedstock and biomass utilization.
2. Based on human and animal nutritional metabolism and physiological functions, developing key technologies for biological synthesis and application of new microbial proteins, functional peptides, nucleotides, trace elements and other nutrients.
Xin Wu, born in 1979, member of CPC, Professor, Ph.D., Doctoral supervisor, researcher at National Synthetic Biology Innovation Center, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences (TIB, CAS), PI of Biological Synthesis of Nutritional Resources Research Group. He obtained a Ph.D. from University of Chinese Academy of Sciences in 2010, and successively served as Assistant Professor, Associate Professor, and Professor at Institute of Subtropical Agriculture, CAS. He was a visiting scholar at French National Institute for Agricultural Research (INRA) and Erasmus University Medical Center in the Netherlands. Since 2021 he has been working as a Professor at TIB, CAS. He was selected into the “National High-level Personnel of Special Support Program”, “National Program for Support of Youth Scientific and Technological Innovation Leaders” and other programs.
His research focuses on microbial and nutritional resource development and their application in animal feed and food. He undertakes national key R&D projects, provincial and ministerial scientific and technological innovation projects. He has authorized 33 invention patents and published over 200 papers in journals like Bioresource Technology, Microbiome, Food & Function, Animal Nutrition, etc., with over 180 papers indexed in SCI. As the first three contributors, he has won 8 national, ministerial and provincial awards, including the National Natural Science Award Second Prize, the Chinese Academy of Sciences Science and Technology Advancement Award, the Chinese Agricultural Science and Technology Award, and the Provincial Invention Award First Prize. His main social positions include Council Member of Chinese Society of Animal Science, Secretary General of Trace Element and Food Chain Branch, etc.
1. Second Prize, National Natural Science Award (No.3 contributor), 2016
2. First Prize, Hunan Provincial Technology Invention Award (No.2 contributor), 2017
3. Second Prize, CAS Science and Technology Promotion Development Award (No.2 contributor), 2018
4. First Prize, China Agricultural Science and Technology Award (No.3 contributor), 2015
5. First Prize for Innovation Team, China Agricultural Science and Technology Award (No.4 contributor), 2021
6. Excellent Graduate Supervisor Team, provincial level, 2018
7. Excellent Young Scientific and Technological Talent of Changsha, municipal level, 2019
1. Gao L, Meng J, Wuling Dai, Zhaokun Zhang, Haofan Dong, Qianqian Yuan, Wuyuan Zhang, Liu SG, Wu Xin*. Deciphering cell wall sensors enabling the construction of robust P. pastoris for single-cell protein production. Biotechnology for Biofuels and Bioproducts,2023 DOI: 10.1186/s13068-023-02428-7
2. Meng Jiao, Liu Shufan, Gao Le, Hong Kai, Liu Shuguang, Wu Xin*. Economical production of Pichia pastoris single cell protein from methanol at industrial pilot scale. Microbial Cell Factories, 2023, 22: 198
3. Le Gao, Zhuohang Yu, Shengjie Wang, Yuejie Hou, Shouchang Zhang, Chichun Zhou*, Wu Xin*. A new paradigm in lignocellulolytic enzyme cocktail optimization: free from expert-level prior knowledge and experimental datasets. Bioresource Technology, 2023, (388): 29758
4. Yingying Feng, Teketay Wassie, Renyou Gan*, Xin Wu*. Structural Characteristics and Immunomodulatory Effects of Sulfated Polysaccharides Derived from Marine Algae. Critical Reviews in Food Science and Nutrition, 2023, 63: 7180–7196
5. Le Gao, Yi Jiang, Kai Hong, Xiaoyi Chen*, Wu, Xin*. Glycosylation of cellulase: A novel strategy for improving cellulase. Critical reviews in biotechnology, 2023, Doi:10.1080/07388551.2022.2144117
6. Shujin Wang*, Wei Fu, Xueya Zhao, Xiaojiao Chang, Hujun Liu, Lin Zhou, Jian Li, Rui Cheng, Xin Wu*, Xi Li*, Changpo Sun*. Mycotoxin disturbs the reproductive-immune axis: the role of gut microbial metabolites. Microbiome, 2022, 10:234
7. Teketay Wassie, Xinyi Duan, Chunyan Xie, Ruxia Wang, Xin Wu*. Dietary Enteromorpha polysaccharide-Zn supplementation regulates amino acid and fatty acid metabolism by improving the antioxidant activity in chicken. Journal of Animal Science and Biotechnology, 2022, 13: 18
8. Lumin Gao, Gangyi Liu, Hongling Wang, Wassie Teketay, Xin Wu*. Maternal pyrimidine nucleosides supplementation regulates fatty acid, amino acid and glucose metabolism of offspring. Animal Nutrition, 2022, 11: 309-321
9. Chunyan Xie, Yumei Zhang, Kaimin Niu, Xiaoxiao Liang, Haihua Wang, Junwei Shan, Xin Wu*. Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets. Animal Nutrition, 2021, 7(3): 641-649
10. Yin Jie, Yuying Li, Hui Han, Shuai Chen, Jing Gao, Gang Liu, Xin Wu*, Jinping Deng, Xingguo Huang, Rejun Fang, Tiejun Li*, Russel J. Reiter, Guoqiang Zhu, Wenkai Ren*, Yulong Yin. Melatonin improves lipid metabolism by reprograming gut microbiota and microbiota-derived acetic acid. Journal of Pineal Research, 2018, 65: e12524
1. National Key R&D Program “Key Technologies and New Product Development for Biological Protein Synthesis from Single Carbon Feedstocks”, 2021.12-2024.11
2. Tianjin Innovation Promotion Action Plan, “R&D of Key Technologies for Evaluation and Application of Functional Feed Proteins”, 2021.3-2024.2
3. International Joint Research Program for the Cooperation Consortium of the Belt and Road, “Precision Fermentation of Chinese Herbal Medicine Based on Synthetic Biology and Its Application”, 2021.12-2024.12
4. CAS Strategic Priority Research Program “Key Technologies and Industrial Demonstration for High-Quality Feed Protein Manufacturing”, 2023.11-2026.10
5. NSFC, “Mechanism of UMP Regulating Intestinal Stem Cell Proliferation, Differentiation and Mucosal Barrier Function”, 2023.01-2026.12
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