Industrial Protein Science and Biocatalytic Engineering
Feng Jinhui

Name: Feng Jinhui

Title: Professor

Tel: 0086-22-24828723

E-mail: feng_jh@tib.cas.cn

Research Interest

1.    The discovery and development of biocatalysts in chiral synthsis.

2.    The research in of chiral recognition mechanism in biosynthesis.

3.    The application of biocatalysts in organic synthesis.

Education & Professional Experience

Education

1997 – 2001, Bachelor of Science in Microbiology, Shandong University, Jinan, China

2001 – 2004Master of Science in Microbiology and Biotechnology, State Key Lab of Microbial Technology

Thesis title: Purification of Flavin Reductase from Mycobacterium goodii and Biodesulfurization of Gasoline

2004 – 2007Ph.D. in Microbiology, State Key Lab of Microbial Technology (Prof. Dr. Ping Xu), Jinan Shandong, China

Dissertation title: Desulfurization and Characterization of the Cell Surface on Rhodococcus erythropolis and Mycobacterium goodii

Professional Experience

2001 - 2008, Shandong University, China, State Key Laboratory of Microbiology (Laboratory of Dr. Ping Xu).


2008 - 2011, Postdoc at National Center for Toxicological Research, Division of Microbiology (Laboratory of Dr. Huizhong Chen). 

2011 - 2020, Associate professor at Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences.

2020 -  , Professor at Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences.

Selected Publications

  1. Liu Yiyin; Zhu Liangyan; Li Xuemei; Cui Yunfeng; Roosta Atefeh; Feng Jinhui; Chen Xi; Yao Peiyuan; Wu Qiaqing; Zhu Dunming. Photoredox/Enzymatic Catalysis Enabling Redox-Neutral Decarboxylative Asymmetroc C-C Coupling for Asymmetric Synthesis of Chiral 1,2-Amino Alcohols,JACS Au, 2023, https://doi.org/10.1021/jacsau.3c00366.
  2. Feng Jinhui; Wu Qiaqing; Zhu Dunming; Ma Yanhe. Biotransformation Enables Innovations Toward Green Synthesis of Steroidal Pharmaceuticals, ChemSusChem, 2022, 15(9):e202102399.
  3. Song Mengkun; Zhang Xuemei; Liu Weidong; Feng Jinhui; Cui Yunfeng; Yao Peiyuan; Wang Min; Guo Rey-Ting; Wu Qiaqing; Zhu Dunming. 2,3-Dihydroxybenzoic Acid Decarboxylase from Fusarium oxysporum: Crystal Structures and Substrate Recognition Mechanism, ChemBioChem, 2020, 21: 2950-2956
  4. Liu Na; Feng Jinhui; Zhang Rui; Chen Xi; Li Xuemei; Yao Peiyuan; Wu Qiaqing; Ma Yanhe; Zhu Dunming. Efficient microbial synthesis of key steroidal intermediates from bio-renewable phytosterols by genetically modified Mycobacterium fortuitum strains, Green Chemistry, 2019, 21(15): 4076-4083.
  5. Lu Wei; Feng Jinhui; Chen Xi; Bao Yun-Juan; Wang Yu; Wu Qiaqing; Ma Yanhe; Zhu Dunming. Distinct regioselectivity of fungal P450 enzymes for steroidal hydroxylation, Applied and Environmental Microbiology, 2019, 85(18): e01182-19.