2020/07- , Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Senior engineer
2014/04-2020/06,Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Research associate/Engineer
2011/04-2014/03,Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Research assistant
2008/09-2010/12, School of Biotechnology, Jiangnan University, Microbiology, Master
2004/09-2008/06, College of Life Sciences, Dezhou University, Biotechnology, Bachelor
1. Third prize of the 8th China Innovation Challenge: Bio-manufacturing Technology Special Competition, 2023.11
2. Outstanding graduate of Shandong Province, 2008.6
I. Academic papers
1. Cai NY#, Chen JZ#, Gao N, Ni XM, Lei Y, Pu W, Wang LX, Che B, Fan LW, Zhou WJ, Feng JH, Wang Y, Zheng P, Sun JB. Engineering of the DNA replication and repair machinery to develop binary mutators for rapid genome evolution of Corynebacterium glutamicum. Nucleic Acids Res. 2023, 51: 8623-8642.
2. Pu W#, Chen JZ#, Liu P#, Shen J, Cai NY, Liu BY, Lei Y, Wang LX, Ni XM, Zhang J, Liu J, Zhou YY, Zhou WJ, Ma HW, Wang Y, Zheng P, Sun JB. Directed evolution of linker helix as an efficient strategy for engineering LysR-type transcriptional regulators as whole-cell biosensors. Biosens Bioelectron. 2023, 222: 115004.
3. Pu W#, Chen JZ#, Zhou YY, Qiu HM, Shi T, Zhou WJ, Guo X, Cai NY, Tan ZJ, Liu J, Feng JH, Wang Y, Zheng P, Sun JB. Systems metabolic engineering of Escherichia coli for hyper-production of 5-aminolevulinic acid. Biotechnol Biof Biop. 2023, 16: 31.
4. Zhou YY#, Chen JZ#, Pu W, Cai NY, Che B, Yang JX, Wang MM, Zhong SS, Zuo XT, Wang DP, Wang Y, Zheng P, Sun JB. Development of a growth-coupled selection platform for directed evolution of heme biosynthetic enzymes in Corynebacterium glutamicum. Front Bioeng Biotechnol. 2023, 11: 1236118.
5. Chen JZ, Wang Y, Zheng P, Sun JB. Engineering synthetic auxotrophs for growth-coupled directed protein evolution. Trends Biotechnol. 2022, 40: 773-776.
6. Huang JW#, Chen JZ#, Wang Y, Shi T, Ni XM, Pu W, Liu J, Zhou YY, Cai NY, Han SY, Zheng P, Sun JB. Development of a hyperosmotic stress inducible gene expression system by engineering the MtrA/MtrB-dependent NCgl1418 promoter in Corynebacterium glutamicum. Front. Microbiol. 2021, 12: 718511.
7. Chen JZ#, Wang Y#, Guo X, Rao DM, Zhou WJ, Zheng P, Sun JB, Ma YH. Efficient bioproduction of 5-aminolevulinic acid, a promising biostimulant and nutrient, from renewable bioresources by engineered Corynebacterium glutamicum. Biotechnol Biofuels. 2020, 13: 41.
8. Li MY#, Chen JZ#, Wang Y, Liu J, Huang JW, Chen N, Zheng P, Sun JB. Efficient multiplex gene repression by CRISPR-dCpf1 in Corynebacterium glutamicum. Front Bioeng Biotechnol. 2020, 8: 357.
9. Zhu CC#, Chen JZ#, Wang Y, Wang LX, Guo X, Chen N, Zheng P, Sun JB, Ma Y. Enhancing 5-aminolevulinic acid tolerance and production by engineering the antioxidant defense system of Escherichia coli. Biotechnol Bioeng. 2019, 116: 2018-2028.
10. Sun DH#, Chen JZ#, Wang Y, Li MY, Rao DM, Guo YM, Chen N, Zheng P, Sun JB, Ma YH. Metabolic engineering of Corynebacterium glutamicum by synthetic small regulatory RNAs. J Ind Microbiol Biotechnol. 2019; 46: 203-208.
11. Zhang LL#, Chen JZ#, Chen N, Sun JB, Zheng P, Ma YH, Cloning of two 5-aminolevulinic acid synthase isozymes HemA and HemO from Rhodopseudomonas palustris with favorable characteristics for 5-aminolevulinic acid production, Biotechnol Lett. 2013, 35: 763-768.
12. Chen JZ, Tao GJ, Wang XY, Construction of an Escherichia coli mutant producing monophosphoryl lipid A, Biotechnol Lett. 2011, 33: 1013-1019.
II. International Patants
1. Zheng Ping; Chen Jiuzhou; Sun Jibin; Cai Ningyun; Guo Xuan; Zhou Wenjuan; Liu Pi; Liu Jiao; Ma Yanhe. Pyruvate dehydrogenase mutant and method for producing, WO2023284419A1.
2. Zheng Ping; Chen Jiuzhou; Huang Jingwen; Sun Jibin; Zhou Wenjuan; Liu Jiao; Wang Yu; Shi Tuo; Ma Yanhe. Polynucleotide having promoter activity and use thereof in production of target compounds, WO2022152036A1.
3. Sun Jibin; Chen Jiuzhou; Zheng Ping; Zhou Wenjuan; Guo Xuan; Shi Tuo; Liu Jiao; Ma Yanhe. Microorganism that produces lysine and method for producing, WO2021143727A1.
4. Zheng Ping; Chen Jiuzhou; Pu Wei; Sun Jibin; Wu Xinyang; Ma Yanhe. 5-aminolevulinic acid high-yield bacterial strain, preparation method and use thereof, US10975400B2.
1. National Natural Science Foundation of China (32000023)
2. Sub-project of National Key Research and Development Program of China (2021YFC2100900)
3. Sub-project of Key R&D Program of Shandong Province (2021CXGC010602)
4. Sub-project of Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project (TSBICIP-KJGG-005)