Research on high-throughput editing and screening technology relying on automation equipment.

2002/09-2006/07  Qufu Normal University, Department of Life Sciences, Qufu, China, Bachelor   

2006/09-2008/07  Jilin University, Department of Molecular Plant Pathology, Changchun, China, Master 

2008/10-2020/07，Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Engineer

2020/07-  , Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China, Senior Engineer

Selected as "Technical Support Talents of the Chinese Academy of Sciences in 2021"

Received the title of "Outstanding Individual of the Institute's Two Level Public Technology Center in 2021";

In 2023, won the title of the fourth "Science Park Master" of the Chinese Academy of Sciences (team honor)

1、 Yanmei Guo, Ping Zheng, and Jibin Sun. Aspergillus niger as a potential cellular factory: prior knowledge and key technology. Chin J Biotech 2010, October 25; 26(10): 1410−1418

2、 YANG Xiao-tao, GUO Yan-mei, ZENG Xiang-feng, MAN Yun, ZHENG Ping, WANG Chang-lu , SUN Ji-bin. Characterization of the Hyperproduction Process of Citric Acid by Aspergillus niger and the Formation of Glyoxylic Acid, Modern Food Science and Technology 2011, Vol.27, No.10

3、 LIU Jin-liang，GUO Yan-mei，ZHENG Ming，ZHANG Shi-hong，PAN Hong-yu. Construction of cDNA Library from Apothecium of Sclerotinia sclerotiorum Identification of SsMADS Gene by EST Sequencing. Journal of Jilin University ,2010，Vol. 48 No. 4

4、 XIE L-i qin, GUO Yan-mei, ZHAO Zeng-lin, YU Hu-i mei, YIN Jun-hua, PAN Hong-yu .Research on Application and Biological Characteristics of Verticillium lecanii Strains in Changchun. Journal of Jilin Agricultural University 2008 , 30(6):782 ～ 788

5、 Ye Liu, Ruoyu Wang, Jiahui Liu, Hui Lu, Haoran Li, Yu Wang, Xiaomeng Ni, Junwei Li, Yanmei Guo, Hongwu Ma, Xiaoping Liao*, Meng Wang*，(2022) Base editor enables rational genome-scale functional screening for enhanced industrial phenotypes in Corynebacterium glutamicum，Sci Adv，8(35):eabq2157

6、 Jiao Liu, Moshi Liu, Tuo Shi, Guannan Sun, Ning Gao, Xiaojia Zhao, Xuan Guo, Xiaomeng Ni, Qianqian Yuan, Jinhui Feng, Zhemin Liu, Yanmei Guo, Jiuzhou Chen, Yu Wang, Ping Zheng, Jibin Sun, CRISPR-assisted rational flux-tuning and arrayed CRISPRi screening of an L-proline exporter for L-proline hyperproduction. NATURE COMMUNICATIONS | (2022) 13:891

7、 Defei Liu, Zixiang Xu, Jingen Li, Qian Liu,Qianqian Yuan, Yanmei Guo, Hongwu Ma, Chaoguang Tian. Reconstruction and analysis of genome‐scale metabolic model for thermophilic fungus Myceliophthora thermophile. Biotechnol Bioeng. 2022;1–12.

8、 Yu Wang, Haijiao Cheng, Yang Liu, Ye Liu, Xiao Wen, Kun Zhang, Xiaomeng Ni, Ning Gao, Liwen Fan, Zhihui Zhang, Jiao Liu, Jiuzhou Chen, Lixian Wang, Yanmei Guo, Ping Zheng, Meng Wang, Jibin Sun & Yanhe Ma，In-situ generation of large numbers of genetic combinations for metabolic reprogramming via CRISPR-guided base editing. NATURE COMMUNICATIONS | (2021) 12:678

9、 Sili Yu, Marcus A. Price, Yu Wang, Yang Liu, Yanmei Guo, Xiaomeng Ni, Susan J Rosser, Changhao Bi, Meng Wang. CRISPR-dCas9 mediated cytosine deaminase base editing in Bacillus subtilis, ACS Synthetic Biology 2020, 9, 1781−1789

10、 Xiao Wen, Yue Zhang , Haijiao Cheng, Jingjing An, Yanmei Guo , Lixian Wang , Meng Wang. A CRISPR/dCas9-assisted system to clone toxic genes in Escherichia coli， BBA General subjects BBA - General Subjects 1865 (2021) 129994

11、 Yu Wang, Ye Liu, Jiao Liu, Yanmei Guo, Liwen Fan, Xiaomeng Ni, Xiaomei Zheng, Meng Wang, Ping Zheng, Jibin Sun, Yanhe Ma. MACBETH: multiplex automated Corynebacterium glutamicum base editing method Metabolic Engineering, 47 (2018) 200–210  

12、 Xiaowei Wang, Qinggang Li, Cunmin Sun, Zhen Cai , Xiaomei Zheng, Xuan Guo, Xiaomeng Ni, Wenjuan Zhou, Yanmei Guo, Ping Zheng, Ning Chen, Jibin Sun, Yin Li, Yanhe Ma.  GREACEassisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli, Microbial Cell Factories (2019) 18:106  

13、 Fengyu Kou . Jing Zhao . Jiao Liu . Cunmin Sun . Yanmei Guo, Zijian Tan, Feng Cheng, Zhimin Li, Ping Zheng, Jibin Sun. Enhancement of the thermal and alkaline pH stability of Escherichia coli lysine decarboxylase for efficient cadaverine production. Biotechnol Lett. 2018 Apr;40(4):719-727

1. Presided over one technical innovation project of instrument and equipment function development of the Chinese Academy of Sciences

2. Project leader: Tianjin Synthetic Biotechnology Innovation Capability Enhancement Action 1

3. Sub project leader: Tianjin Synthetic Biotechnology Innovation Capability Enhancement Action 1