My research interests are focoused on computational biology, including bioinformatics, computational systems and synthetic biology. Specialize in: Processing of Omics data; Modeling, analysis and design of biomolecular networks, such as metabolic networks and regulatory networks; Design of synthetic pathways and parts of pathways for chemicals production.
2009-Present Assistant & Associate Investigator, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
2006-2009 Postdoc, State Key Laboratory of Bioelectronics, Southeast University, Nanjing, Chin
2001-2006 Ph.D. School of Electron & Information, North-western Politechnical University, China
1998-2001 M.S. Faculty of Science, Jiangsu University, China
1993-1995 B.S. Department of Physics, Hefei Normal University, China
2001 Master Thesis “Research and its Application of Structural Topological Optimization” wins excellent Master Thesis of Jiangsu University.
At present, he has published nearly 30 Chinese and English papers in computational biology and applied mathematics as the first author, together with nearly 50 co-authored papers.
1. Xu Zixiang, et.al.. In Silico Genome- Scale Reconstruction and Analysis of the Shewanella loihica PV-4 Metabolic Network. Journal of Biological Systems. 2018,
26(3): 373–397
2. Xu Zixiang, et.al.. Find_tfSBP: find thermodynamics feasible and smallest balanced pathways with high yield from large-scale metabolic network. Scientific
Reports. 2017, 7:17334
3. Xu Zixiang, et.al.. ReacKnock: identifying reaction deletion strategies for microbial strain optimization based on genome-scale metabolic network. PLoS ONE . 2013, 8(12): e72150.
4. Xu Zixiang, et.al.. Reconstruction of whole cell network and design of cell factory. Progress in Biochemistry and Biophysics. 2014,41(2):105~114.
5. Xu Zixiang, et.al.. Genome-Scale Analysis to the Impact of Gene deletion on the Metabolism of E. coli: Constraint-Based Simulation Approach. BMC Bioinformatics. 2009, 10 (Suppl 1): S62.
6. Xu ZiXiang, et.al.. Numerical Method Based On Hamilton System And Symplectic Algorithm To Differential Games. Applied Mathematics And Mechanics (Eng Ed). 2006,27(3):341-346.
As leader: 2 projects of MOST, 1 project of NSFC, 2 projects of Tianjin city
As partner: 1 project of 973, 3 projects of CAS, 1 project of Tianjin city