Associate Professor/Senior Engineer
Xu Zixiang

Title:Xu Zixiang

Tel:0086-22-24828721

E-mail:xu_zx(AT)tib.cas.cn

Research Interest

My research interests are focoused on computational biology, including bioinformatics, computational systems and synthetic biology. Specialize in: Processing of Omics data; Modeling, analysis and design of biomolecular networks, such as metabolic networks and regulatory networks; Design of synthetic pathways and parts of pathways for chemicals production.

Education & Professional Experience

2009-Present  Assistant & Associate Investigator, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

2006-2009  Postdoc, State Key Laboratory of Bioelectronics, Southeast University, Nanjing, Chin

2001-2006  Ph.D. School of Electron & Information, North-western Politechnical University, China

1998-2001  M.S. Faculty of Science, Jiangsu University, China

1993-1995  B.S. Department of Physics, Hefei Normal University, China

Honors and Awards

2001  Master Thesis “Research and its Application of Structural Topological Optimization” wins excellent Master Thesis of Jiangsu University.

Selected Publications

At present, he has published nearly 30 Chinese and English papers in computational biology and applied mathematics as the first author, together with nearly 50 co-authored papers.

1. Xu Zixiang, et.al.. In Silico Genome- Scale Reconstruction and Analysis of the Shewanella loihica PV-4 Metabolic Network. Journal of Biological Systems. 2018,

26(3): 373–397

2. Xu Zixiang, et.al.. Find_tfSBP: find thermodynamics feasible and smallest balanced pathways with high yield from large-scale metabolic network. Scientific

Reports. 2017, 7:17334

3. Xu Zixiang, et.al.. ReacKnock: identifying reaction deletion strategies for microbial strain optimization based on genome-scale metabolic network.  PLoS ONE .  2013, 8(12): e72150.

4. Xu Zixiang, et.al.. Reconstruction of whole cell network and design of cell factory.  Progress in Biochemistry and Biophysics.  2014,41(2):105~114.

5.  Xu Zixiang, et.al.. Genome-Scale Analysis to the Impact of Gene deletion on the Metabolism of E. coli: Constraint-Based Simulation Approach. BMC  Bioinformatics. 2009, 10 (Suppl 1): S62.

6. Xu ZiXiang, et.al.. Numerical Method Based On Hamilton System And Symplectic Algorithm To Differential Games. Applied Mathematics And Mechanics (Eng Ed).  2006,27(3):341-346.

Project

As leader: 2 projects of MOST, 1 project of NSFC, 2 projects of Tianjin city

As partner: 1 project of 973, 3 projects of CAS, 1 project of Tianjin city