The main research areas including the development and application of industrial enzyme preparations, new enzyme gene mining, protein biosynthesis, industrial strain construction, microbial application technology, etc.

2018/11 -, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences，associate researcher

2014/08 - 2018/11，Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences，assistant researcher

2012/10 - 2014/07，Academy of agricultural planning and engineering, MARA，post-doctor

2009/09 - 2012/10，Tianjin University of Science and Technology，fermentation engineering，doctor

Member of enzyme preparation a council, Chinese Society of Food Science and Technology.

Guest Editor of Special Issue "Biotechnological Advances in Industrial Enzymes and Green Bioprocessing" of Bioengineering Journal.

Won the Tianjin Patent Award Excellence Award (ranked 3rd).

1、Hongchen zheng^#,*, Wenju Shu^#, Xiaoping Fu^#, Xingya Zhao, Shibin Yang, Jianyong Xu^*, Hui Song^*, Yanhe M. A pyruvate-centered metabolic regulation mechanism for the enhanced expression of exogenous genes in Escherichia coli. Int J Biol Macromol. 2022, 203:58-66.

2、Jie Zhen^#, Hongchen Zheng^#,*, Xingya Zhao^#, Xiaoping Fu, Shibin Yang, Jianyong Xu^*, Hui Song^*, Yanhe Ma. Regulate the hydrophobic motif to enhance the non-classical secretory expression of Pullulanase PulA in Bacillus subtilis. Int J Biol Macromol. 2021, 193: 238-246.

3、ShiBin Yang^#, HongChen Zheng^#,*, JianYong Xu, XingYa Zhao, WenJu Shu, XiangMing Li, Hui Song^*, YanHe Ma^*. A new biotransformation mode of zearalenone identified in Bacillus subtilis Y816 revealing a novel ZEN conjugate. Journal of Agricultural and Food Chemistry. 2021, 69(26): 7409-7419.

4、Zhao X^#, Zheng H^#,*, Zhen J, Shu W, Yang S, Xu J, Song H^*, Ma Y^*. Multiplex genetic engineering improves endogenous expression of mesophilic α-amylase gene in a wild strain Bacillus amyloliquefaciens 205. Int J Biol Macromol. 2020, 165(Pt A): 609-618.

5、Zhao X^#, Xu J^#, Tan M^#, Zhen J, Shu W, Yang S, Zheng H*, Ma Y^*, Song H^*. High copy number and highly stable Escherichia coli-Bacillus subtilis shuttle plasmids based on pWB980. Microb Cell Fact. 2020, 19(1): 25.

6、Zeng Y^#, Xu J^#, Fu X, Tan M, Liu F, Zheng H^*, Song H^*. Effects of different carbohydrate-binding modules on the enzymatic properties of pullulanase. Int J Biol Macromol. 2019, 137:973-981.

7、Zheng H^#, Yu Z^#, Shu W^#, Fu X, Zhao X, Yang S, Tan M, Xu J, Liu Y^*, Song H^*. Ethanol effects on the overexpression of heterologous catalase in Escherichia coli BL21 (DE3). Appl Microbiol Biotechnol. 2019, 103(3): 1441-1453.

8、Zhao X^#, Xu J^#, Tan M, Yu Z, Yang S, Zheng H^*, Song H^*. Construction of a plasmid interspecific transfer system in Bacillus species with the counter-selectable marker mazF. J Ind Microbiol Biotechnol. 2018, 45(6):417-428.

9、Yu Z^#, Zheng HC^#, Zhao X, Li S, Xu J, Song H^*. High level extracellular production of a recombinant alkaline catalase in E. coli BL21 under ethanol stress and its application in hydrogen peroxide removal after cotton fabrics bleaching. Bioresour Technol. 2016, 214: 303-310.

10、Zheng Hongchen^#, Yihan Liu^#, Xiaoguang Liu, Yang Han, Jianling Wang, Fuping Lu^*. Overexpression of a Paenibacillus campinasensis xylanase in Bacillus megaterium and its applications to biobleaching of cotton stalk pulp and saccharification of recycled paper sludge. Bioresource Technology. 2012, 125: 182-187.