Introduction

Biodesign Center (BDC) is an interdisciplinary research center established at the end of 2019 by integrating multiple computational research groups at TIB. The vision is to empower bioscience with theoretical models and make computational design the core of biotechnology R&D. We develop new algorithms and tools to solve biological problems by adopting novel artificial intelligence methods and computational techniques. Through cross-disciplinary research, we aim to train a new generation of dry biologists and revolutionize the industrial biotechnology R&D paradigm.

BDC develops biological databases, mathematical models, algorithms and software tools for the precision design of enzymes, metabolic pathways and artificial cell factories. BDC manages the TIB high-performance computing cluster (TIBHPC) and the data center for biomanufacturing (DMDC), providing services on computing power, data management and analysis. Based on the established Biodesign platform, BDC collaborated closely with experimental biologists to provide computational support on enzyme, pathway and strain design.