1. Design and optimization of biocatalytic reaction process
2. Enzyme immobilization
2023.10- , Senior Engineer, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
2009.11-2023.10, Assistant Researcher, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
2009.11-2014.04, Research interns, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
2008.06-2009.04, Assistant Researcher, WuXi AppTec, Tianjin, China.
2005.09-2008.06, Master of Organic Chemistry, Hebei Normal University, Shijiazhuang, China.
1. Jianjiong Li,# Shanshan Yu,# Yingang Wang, Peiyuan Yao,* Qiaqing Wu,* Dunming Zhu*, Simultaneous Preparation of (S)-2-Aminobutane and d-α-Amino Acids via Biocatalytic Transamination at High Substrate Concentration, Org. Process Res. Dev., 2022, 26, 2013-2020.
2. Linsong Yang,# Jianjiong Li,# Zefei Xu, Peiyuan Yao,* Qiaqing Wu, Dunming Zhu,* Yanhe Ma*, Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2‑Arylethylamines via a Chemoenzymatic Approach, Org. Lett., 2022, 24, 6531-6536.
3. Jiacheng Li, # Jianjiong Li, # Yunfeng Cui, Min Wang, Jinhui Feng, Peiyuan Yao,* Qiaqing Wu, Dunming Zhu*, Asymmetric Synthesis of Both Enantiomers of Dimethyl 2-Methylsuccinate by the Ene-Reductase-Catalyzed Reduction at High Substrate Concentration, Catalysts, 2022, 12, 1133.
4. Jianjiong Li, Xi Chen, Yunfeng Cui, Weidong Liu, Jinhui Feng, Qiaqing Wu,⁎ Dunming Zhu⁎, Enzymatic synthesis of d-alanine from a renewable starting material by co-immobilized dehydrogenases,Process Biochemistry, 2018, 66, 126-132.
5. Peiyuan Yao, # Jianjiong Li, # Jing Yuan, Chao Han, Xiangtao Liu, Jinhui Feng, Qiaqing Wu,* Dunming Zhu*, Enzymatic Synthesis of a Key Intermediate for Rosuvastatin by Nitrilase-Catalyzed Hydrolysis of Ethyl (R)-4-Cyano-3-hydroxybutyate at High Substrate Concentration, ChemCatChem, 2015, 7, 271-275.
6. Dunming Zhu, Jianjiong Li, Qiaqing Wu, Marine enzymes for biocatalysis (Stereoselective synthesis using marine enzymes), Woodhead publishing, 2013.